Affiliated Faculty
This list of affiliated investigators can help you identify potential research mentors at the University of Pittsburgh. PSTP students can, and do, work with mentors not on this list, but the investigators featured below have expressed interest in hosting PSTP students in their laboratories.
Protein “quality control”, diseases associated with misfolded proteins, and drug treatments for these diseases
We are interested in using the tools of structural biology to a) uncover the molecular adaptations that proteins of a highly diversified signaling TGF-beta signaling family have acquired to achieve their unique functions and b) leverage this knowledge to to develop targeted therapies for treating human disease, including soft tissue cancers and tissue fibrosis driven by dysregulated TGF-beta signaling and hereditary hemorrhagic telangiectasia caused by mutations in the receptors and co-receptors for BMP9 and BMP10.
Non-receptor protein-tyrosine kinase structure, regulation and signal transduction in cancer, AIDS, and embryonic stem cell biology
Repair of DNA damage in nuclear and mitochondrial genomes; Structure and function of nucleotide excision repair proteins