Affiliated Faculty

This list of affiliated investigators can help you identify potential research mentors at the University of Pittsburgh. PSTP students can, and do, work with mentors not on this list, but the investigators featured below have expressed interest in hosting PSTP students in their laboratories.

Sameer Agnihotri, PhD
Research Areas Research Summary

The Brain Tumor Biology and Therapy Laboratory studies pediatric and adult high-grade gliomas (HGG)—focusing on brain tumor signing, glioma metabolism and using genomics to identify novel and effective therapies.

Christopher Bakkenist, PhD
Research Areas Research Summary

Identify phosphorylations, dephosphorylations and acetylations that regulate ATM activity in vivo

Kara Bernstein, PhD
Research Areas Research Summary

Repair of DNA damage is crucial to prevent mutations observed in cancer. Using live cell imaging, we study how double-strand breaks are repaired.

Robert Binder, PhD
Research Areas Research Summary

The mechanisms of cross-priming of antigens during immune responses to cancer, viruses and autoimmunity

Ronald Buckanovich, MD, PhD
Research Areas Research Summary

Tumor microenvironment, Cancer stem cells, novel therapeutics for cancer

Timothy F. Burns, MD, PhD
Research Areas Research Summary

Development of targeted therapies for KRAS mutant NSCLC; Reactivation of OIS and apoptosis; Mechanisms of acquired resistance to targeted agents

Yuan Chang, MD
Research Areas Research Summary

The study of human tumor viruses

Lan Coffman, MD, PhD
Research Areas Research Summary

Stomal Interactions critical to the survival, growth, and spread of ovarian cancer

Greg Delgoffe, PhD
Research Areas Research Summary

The metabolic regulation of T cell function, with a specific focus of those T cells that infiltrate the nutrient-poor tumor microenvironment

Umamahefwar Duvvuri, MD, PhD
Research Areas Research Summary

The molecular landscape of head and neck cancers; Tying this to technical innovations that improve surgical care for these patients

Robert Ferris, MD, PhD
Research Areas Research Summary

Mechanisms of immune escape and clinical translation to therapeutic cancer immunotherapy trials

Deborah Galson, PhD
Research Areas Research Summary

Roles of signal transduction pathways, transcription factors, and chromatin epigenetics in pathological changes in osteoclasts and osteoblasts in cancer-induced bone disease and Paget’s disease of bone

Adrian Lee, PhD
Research Areas Research Summary

Molecular profiling (genomic, transcriptomic, proteomic) of women’s cancers, mouse modeling, and predictive biomarkers for targeted therapy

Jason Lohmueller
Research Areas Research Summary

The Lohmueller lab works on developing genetic engineering approaches to augment adoptive cell therapy (ACT) for the treatment of cancer.

Linda McAllister-Lucas, MD, PhD
Research Areas Research Summary

Mechanisms by which dysregulated intracellular signaling promotes inflammation and neoplasia

Patrick S. Moore, MD, MPH
Research Areas Research Summary

The study of human tumor viruses

Steffi Oesterreich, PhD
Research Areas Research Summary

Hormone response and treatment resistance in breast and ovarian cancer, including the analysis of aberrant genetic and epigenetic changes

Edward Prochownik, MD, PhD
Research Areas Research Summary

Metabolic, molecular and biochemical changes in animal models of pediatric and adult liver cancers and how best to capitalize on these for therapeutic purposes

Saumendra Sarkar, PhD
Research Areas Research Summary

Two related aspects involved in interferon production in the context of infectious disease and cancer: Modulation of IFN induction during RNA and DNA virus infections; Mechanisms and consequences of interferon induction in specific tumors

Kathy Shair, PhD
Research Areas Research Summary

 Studying Epstein-Barr virus molecular pathogenesis in the nasopharynx using 3-D cell air-liquid interface culture models.

Richard Steinman, MD, PhD
Research Areas Research Summary

Mechanisms of white blood cell differentiation & its inhibition in leukemias; Mechanisms of stem cell differentiation & growth control

Anda Vlad, MD, PhD
Research Areas Research Summary

The Vlad lab focuses on the development of new combination therapies for ovarian cancer and identification of new mechanisms of treatment response or resistance.

Lin Zhang, PhD
Research Areas Research Summary

Genetic basis of differential sensitivity to anticancer drugs; Genetic alterations that cause drug resistance; Mechanisms of drug-induced apoptosis