Audrey Kindsfather

Undergraduate Degree: BS
Undergraduate Degree Year: 2015
Undergraduate Institution: University of Richmond
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Academic Status
Year in Program: RY-LOA
Graduate Program:
Research Advisor First Name: Melissa
Research Advisor Last Name: Mann
Research Title/Research Topic: Determination of the methylation of gene promoters in lung cancer cell lines
Current Research Description: Alterations in epigenetic mechanisms, including methylation, can contribute to carcinogenesis by changing the expression of genes necessary for normal cellular functions. Using methylation-specific PCR, I analyzed the methylation of several gene promoters in lung adenocarcinoma and squamous cell carcinoma cell lines, and found that all eight cell lines were methylated at the PTPRT promoter, the PTPRM promoter was not methylated in any of the cell lines, and the promoters of SLC6A3, PIK3IP1, CYP24A1, and CYP27A1 were methylated in a portion of the cell lines.

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